Interferential Current Therapy (ICT): Does It Work?

February 27, 2023by William Bozeman

Interferential Current Therapy (ICT) is a non-invasive therapy that uses electrical muscle stimulation to relieve pain and enhance healing. It is used for a variety of conditions but especially for chronic pain and post-surgical pain. We’ll discuss everything you need to know about ICT and whether it could be an effective treatment for you.

What Is ICT?

Interferential current therapy is a treatment modality where two medium-frequency currents are directed into damaged tissue. The frequencies are set up so that the paths of the currents cross and literally “interfere” with each other. 

Since the body essentially functions using a series of electrical signals across the cells, electrical stimulation can boost the healing response of the body. ICT can promote healing by increasing the hormones and chemicals that facilitate healing. 

ICT can also block pain signals as electrical stimulation can influence the nerves. This is one mechanism by which it can relieve pain, reduce swelling or edema of the damaged tissue, and promote healing of injured muscles. 

How does ICT act? ICT gets delivered via electrodes. While the physics may be a bit complicated, here’s an example. If one electrode delivers at 4000 Hz and its companion at 3900 Hz, the resultant beat frequency would be 100 Hz. 

Usually, the frequency required to contract muscles is between 1 and 100 Hz. Different frequencies produce different contraction responses. A larger frequency at 100 Hz can stimulate the pain gates and close them to painful impulses. 

Without pain, the chemicals that respond to it and cause edema are reduced. This reduces local swelling within damaged tissues and promotes the dilation of blood vessels. The duration of each session with interferential current is somewhere between 10-20 minutes.

Here are the different frequencies used to achieve various effects:

  • 100-150 Hz constant or 90-100 Hz rhythmic frequency is used for pain relief
  • 0-10 Hz rhythmic or 10- 50 Hz rhythmic frequency is used for muscle stimulation
  • 0-100 Hz rhythmic frequency is used for vasodilation as it relaxes the walls of the blood vessels and improves circulation

Earlier models used two electrodes. Modern units have four electrodes that can deliver a rapid series of currents to achieve the same effect in a single sweep. They usually offer frequencies of 1-150 Hz, with a choice of up to 250 Hz or more in others. 

Understanding How ICT Works To Relieve Pain 

ICT is applied with the individual in a comfortable position. Before starting, the skin is cleaned and prepped. Vacuum electrodes or pad electrodes are then placed on the area that is being treated. Two pairs of electrodes are positioned so that the crossing point of the two currents is over the treatment site. Below is a list of the estimated frequency for various tissues:

  • Smooth Muscle: 0-10 Hz
  • Sympathetic Nerves: 1-5 Hz
  • Parasympathetic Nerves: 10-150 Hz
  • Motor Nerves: 10-50 Hz
  • Sensory Nerves: 90-100 Hz
  • Nociceptive Or Pain Fibers: 90-150 Hz

ICT works in four ways. They are listed below:

  • Pain Relief: By stimulating the pain gates at frequencies of 90-150 Hz, the pain sensations are blocked or hidden. At lower frequencies, the opioid receptors can also be activated. Once activated, a person becomes numb to the pain as they cannot perceive the pain. 

Both these pathways can provide significant pain relief. ICT can be used for joint pain, back pain, sciatica, and radicular pain. 

  • Muscle Stimulation: Motor nerves in the muscles can be stimulated at various frequencies. Depending on the desired effect, the stimulation can be changed. At 1 Hz, muscle twitches are possible and tetany or contraction of the muscles can be achieved at 50 Hz. 

However, if you do a sweep at 10-25 Hz, it is possible to increase blood flow, reduce edema, and stimulate the muscles. 

  • Increased Blood Flow: The effect of blood vessel dilation is most likely achieved with one of two mechanisms: muscle contraction or the effect on the sympathetic nerves. 

The first mechanism is the effect of muscle contraction, where ICT contracts the muscles which cause the blood supply to increase in response to the metabolic demand of the muscle. The other mechanism is the effect on the sympathetic nerves which causes the vessels to dilate. 

The role of the sympathetic nervous system is to increase blood supply via vasodilation. ICT stimulates the sympathetic nerves, increasing blood flow. At present, the 10-20 or 10-25Hz frequency sweep has the desired effect of increasing blood supply. 

  • Reduction Of Edema: By blocking pain sensation, the inflammatory chemicals that increase with pain can be suppressed. These chemicals are less painful, so the edema or swelling due to inflammation is reduced. ICT also promotes the resorption of edema fluid, although the exact mechanism is not clear. 
  • Interferential Current Vs. TENS

Interferential current is different from TENS (transcutaneous electrical nerve stimulation). Firstly, interferential current modulates at a much higher frequency at about 4000 Hz compared to TENS at 125 Hz. 

At higher frequencies, the resistance of the skin decreases, so there is a better penetration depth and larger volume of tissue treated. As a result, interferential current therapy can relieve deep seated pain within the tissues as well. ICT also improves circulation which facilitates healing, something that is not possible with TENS.

Clinical Conditions That Can Be Treated With ICT 

ICT can be used for various clinical conditions that cause chronic pain. Here are some of the clinical conditions in different areas of the body that can be targeted with interferential current therapy:


ICT can be used in the neck to treat conditions such as cervical spondylosis, disc herniation, and spinal canal stenosis. All of these conditions can cause severe and chronic pain that is often not relieved with analgesic medications. ICT can suppress pain and block nerve conduction so the perception of pain in the neck is less. 


Disc herniation and spinal canal stenosis are chronic conditions that affect the spine and the back, leading to back pain. Chronic lower back pain that arises due to a nerve impingement, degenerative disc disease, or a herniated disc can also be treated with ICT. 


Osteoarthritis and rheumatoid arthritis are conditions that can affect the knee. Interferential current therapy can be used to treat the pain and also reduce the edema surrounding the affected knee joint. 


Conditions such as a frozen shoulder can be treated with multiple sessions of ICT. If there is an injury to a muscle or ligament in the shoulder, ICT can also effectively treat these conditions as well. 


Pain from nerve conditions such as peripheral neuropathy, neuralgia, or post-herpetic lesions, can also be treated with interferential current therapy. 

Potential Side Effects Of ICT 

While ICT is effective, there are some potential side effects, especially if an individual is new to interferential current therapy. Not everyone may experience these side effects but they are a possibility. Some of the side effects of ICT are listed below: 

  • Skin irritation
  • Headaches
  • Dizziness
  • Muscle spasms
  • Decreased concentration
  • Drowsiness
  • Altered heart rate

Interferential current therapy is mostly safe and without any major side effects. However, there are certain individuals for whom it is not recommended: 

  • ICT is not recommended for pregnant women as the electrical current may harm the baby.
  • ICT is contraindicated for children, especially in areas of epiphyseal growth.
  • ICT may not be used on individuals with an implanted medical device like a pacemaker as it can cause cardiac arrhythmia.
  • ICT may not be used on those with severe dermatitis or where the skin barrier has been broken as this can cause a burn or infection.
  • ICT therapy may not be used on individuals with a bleeding condition or those on blood thinners.
  • ICT may not be recommended for cancer patients.
  • ICT is not recommended for those with epilepsy as it could trigger a seizure.

Neuragenex Can Help You Live A Pain-Free Life

You don’t have to put up with pain – it is possible to live a pain-free life. Neuragenex offers ICT as a non-pharmaceutical, non-opioid, non-drug, nonsurgical, non-invasive, and non-chiropractic treatment for pain. 

If your doctor has not offered interferential current therapy for your pain, then it may be time to ask about your treatment options. 

Find effective and long-lasting relief with Neuragenex

Schedule your consultation today.
William Bozeman

by William Bozeman

William is a healthcare executive, innovator, entrepreneur, inventor, and writer with a wide range of experience in the medical field. William has multiple degrees in a wide range of subjects that give depth to his capability as an entrepreneur and capacity to operate as an innovative healthcare executive. William has an associate degree in electrical technology, two undergraduate degrees in biotechnology and archaeology, an MBA, and attended medical school in Alabama. William took a leave of absence from medical school to open his first biotech lab and serve as the chief science officer, writer, and innovator. William has founded and launched multiple biotech ventures while serving in a range of positions in that field as chief executive officer, chief science officer, chief medical officer, founder, and innovator. William has brought multiple biologic products to market for clinical use applications and written many treatment protocols for application of use and helped pioneer the use of regenerative medicine in the medical field. William's research-based protocols paved the way for widescale procedure use application in the medical field. Many physicians and medical providers still use his protocols in their practice today and have shared their success and techniques with hundreds of physicians and providers. William was one of the first entrepreneurs to actively help integrate regenerative medicine into mainstream healthcare and coached hundreds of physicians and providers across the nation in the use of regenerative medicine.

William has founded and launched a range of new medical businesses and served as an executive in multiple companies in the healthcare field:

  • Multiple biotech and biologic product production labs with robust national and international distribution
  • Multiple high complex clinical toxicology and PCR labs
  • A nationwide allergy and immunotherapy medical service organization with dozens of locations
  • Founded and opened multiple medical practices and medical service programs specializing chronic pain management without medications, surgery, or invasive procedures.

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Copyright 2024 Neuragenex. All rights reserved.